Endometriosis is defined as the presence of endometrial-like tissue outside the uterus, which induces a chronic inflammatory reaction, scar tissue, and adhesions that may distort a woman’s pelvic anatomy. The symptoms of endometriosis include pelvic pain, pain during intercourse, pain during menses, as well as infertility. The principal aims of therapy include relief of symptoms, avoiding progression, and preventing infertility. Current treatments focus on a combination of medical, surgical, and psychological treatments that can improve the quality of life for women with endometriosis. A combination of medical-surgical treatment significantly enhances the fertility potential. Women with endometriosis desiring pregnancy are encouraged to pursue conception efforts.